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Eric J. Topol, M. D

BibliographyEric J. Topol, M.D.BIBLIOGRAPHYOriginal Publications in Scientific Journals1. Moss AJ, Glaser W, Topol EJ:  Atrial tachypacing in the treatment of a patient with primary orthostatic hypotension.  New England Journal of Medicine 302:1456-1457, 1980. [PMID 7374710] 2. Topol EJ, Brodows RD:  Effect of indomethacin on acute insulin release in man.  Diabetes 29:379-383, 1980. [PMID 6769727] 3. Topol EJ, Goldschlager N, Ports T, DiCarlo L, Schiller N, Botvinick E, Chatterjee K:  Hemodynamic benefit of atrial pacing in right ventricular myocardial infarction.  Annals of Internal Medicine 96:594-597, 1982. [PMID 7073152] 4. Topol EJ, Lerman BB:  Hypomagnesemic torsade de pointes.  American Journal
of Cardiology 52:1367-1368, 1983. [PMID 6650429] 5. Lerman BB, Topol EJ, Platia EV, Baughman KL:  Orthostatic atrial tachy-cardia:  Autonomic influence on atrial pacemakers.  American Journal of Cardiology 54:1406-1408, 1984. [PMID 6711447] 6. Topol EJ, Fortuin NJ: Cardiac tumors and carcinoid heart disease.  American -Journal of Medicine 77:950-952, 1984. [PMID 6496552] 7. Topol EJ, Weiss JL, Guzman PA, Dorsey Lima S, Blanck TJJ, Humphrey LJ, Baumgartner WA, Flaherty JT, Reitz BA:  Immediate improvement of dysfunc-tional myocardial segments after coronary revasculari-zation:  detection by intraoperative transesophageal echocardi-ography.  Journal of American College of Cardiology 4:1123-1134, 1984. [PMID 6334108] 8. Collen D, Topol EJ, Tiefenbrunn AJ, Gold HK, Weisfeldt ML, Sobel BE, Leinbach RC, Brinker JA, Ludbrook PA, Yasuda T, Bulkley BH, Robinson AK, Hutter AM, Bell WR, Spadaro JJ, Khaw BA, Grossbard EB:  Coronary thrombo-lysis with -recombinant human tissue type plasminogen activator:  a prospective, randomized, placebo-controlled trial.  Circulation 70: 1012-1017, 1984. [PMID 6388898] 9. Topol EJ, Traill TA, Fortuin NJ:  Hypertensive hypertrophic cardio-myopathy of the elderly.  New England Journal of Medicine 312:277-283, 1985. [PMID 2857050] 10. Topol EJ, Ciuffo AA, Pearson TA, Dillman JJ, Builder S, Grossbard E, Weisfeldt ML, Bulkley BH:  Thrombolysis with recombinant tissue plasminogen activator in atheroscle-rotic, thrombotic occlusion.  Journal of American College of Cardiology 5:85-91, 1985. [PMID 4038373] 11. Topol EJ, Biern R, Reitz B:  Cardiac papillary fibroelastoma and stroke:  Echo-cardio-graphic diagnosis and guide to excision.  American Journal of Medicine 80:129-132, 1986. [PMID 3942145] 12. Topol EJ, Humphrey LS, Borkon MA, Baumgartner WA, Reitz BA, Weiss JL:  Value of intraoperative left ventricular microbubbles detected by transesophageal two dimensional echocardiography in predicting neurologic outcome after cardiac operations.  American Journal of Cardiology 56:773-775, 1985. [PMID 4061300] 13. Topol EJ, Weiss JL, Brinker JA, Bulkley BH, Brin KP, Gottlieb SO, Gerstenblith G, Guerci AD, Flaherty JF, Chandra N, Ouyang P, Gottlieb SH, Becker LB, Weisfeldt ML, Shapiro EP:  Regional wall motion improvement after coronary thrombolysis with recombinant tissue plasminogen activator:  importance of coronary angioplasty.  Journal of American College of Cardiology 6:426-433, 1985. [PMID 3160757] 14. Topol EJ, Eha J, Brin KP, Shapiro EP, Weiss JL, Riegel MB, Gottlieb SO, 
Brinker JB:  Applicability of percutaneous trans-luminal coronary angioplasty to patients with recombinant tissue plasminogen acti-vator mediated thrombo-lysis.  Catheterization and Cardiovascular Diagnosis 11:337-348, 1985. [PMID 2931176] 15. Topol EJ, Myler RK, Stertzer SH:  Selection of dilatation hardware for PTCA –1985.  Catheterization and Cardiovascular Diagnosis 11:629-637, 1985. [PMID 2936462] 16. Topol EJ, Lerman BB, Baughman KL, Platia EV, Griffith LSC:  De novo refrac-tory ventricular tachyarrhythmias after coronary revascu-larization.  American Journal of Cardiology 57:57-59, 1986. [PMID 3484603] 17. Topol EJ, Bell WR, Weisfeldt ML:  Coronary thrombolysis with recombinant tissue-type plasminogen activator:  A hematologic and pharmacologic study.  -Annals of Internal Medicine 103:837-843, 1985. [PMID 3933395] 18. Topol EJ, Fung AY, Kline E, Kaplan L, Landis D, Strozeski M, Burney RE, Pitt B, O’Neill WW:  Safety of helicopter transport and out of--hospital intra-venous fibrinolytic therapy in patients with evolving myocardial infarc-tion.  Catheterization and Cardio-vascular Diagnosis 13:151-155, 1986. [PMID 3089627] 19. Topol EJ, Herskowitz A, Hutchins G:  Massive hemorrhagic myo-cardial infarction after coronary thrombolysis.  American Journal of Medicine 81:339-343, 1986. [PMID 3090880] 20. Fung AY, Lai P, Topol EJ, Bates ER, Bourdillon PDV, Walton JA Jr, Mancini GBJ, Kryski T, Pitt B, O’Neill WW:  Value of percutaneous transluminal coronary angio-plasty after unsuccessful intravenous streptokinase therapy in acute myocardial infarction.  American Journal of- -Cardiology 58:686-691, 1986. [PMID 2945418] 21. Wind BE, Snider RA, Buda AJ, O’Neill WW, Topol EJ, Dilworth LR: Pulsed doppler assessment of left ventricular diastolic filling in coronary artery disease -before and immediately after coronary angioplasty. American Journal of Cardiology 59:1041-1046, 1987. [PMID 2953227] 22. Myler RK, Topol EJ, Shaw RE, Stertzer SH, Clark DA, Fishman-Rosen J, Murphy MC:  Multiple vessel coronary angioplasty:  classifica-tion, results and patterns of restenosis in 494 consecutive patients.  Catheterization and Cardiovascular Diagnosis 13:1-15, 1987. [PMID 2949849] 23. Topol EJ, Morris D, Smalling R, Schumacher R, Taylor CR, Nishikawa A, Liberman HA, Collen D, Tufte ME, Grossbard E, O’Neill WW:  A multicenter, randomized, placebo controlled trial of a new form of intravenous recombi-nant tissue type plasmino-gen activator (Activase) in acute myocardial infarction. Journal of American College of Cardiology 9:1205-1213, 1987. [PMID 2953770] 24. Kircher BE, Topol EJ, O’Neill WW, Pitt B:  Prediction of coronary artery recanalization after intra-venous thrombolytic therapy.  American Journal of Cardiology 59:513-515, 1987. [PMID 3825886] 25. Topol EJ, O’Neill WW, Langburd AB, Walton JA, Bourdillon PVD, Bates ER, Grines CL, Schork MA, Kline E, Pitt B:  A randomized, placebo-controlled trial of intra-venous recombinant tissue type plasminogen activator and emergency coronary angioplasty in patients with acute myocardial infarction.  Circulation 75:420-428, 1987. [PMID 2948735] 26. Walsh DG, Kaplan LR, Burney RE, Topol EJ, O’Neill WW: Use of tissue plas-minogen activator in the emergency department for acute myocardial infarction. Annals of Emergency Medicine 16:243-247, 1987. [PMID 2949679] 27. Topol EJ, Ellis S, Fishman-Rosen J, Leimgruber P, Myler RK, Stertzer SH, 
O’Neill WW, Douglas JS, Roubin G, King SE:  Multi-center study of percu-taneous trans-luminal angioplasty for right coronary artery ostial stenosis.  Journal of American College of Cardiology 9:1214-1218, 1987. [PMID 2953771] 28. O’Neill WW, Topol EJ, Fung AY, Bourdillon PDV, Nicklas JM, Walton JA, Bates ER, Pitt B:  Coronary angioplasty as therapy for acute myocardial infarc-tion:  University of Michigan experience.  Circulation 76(Suppl II):II-79-87, 1987. [PMID 2955959] 29. Pitt B, Topol EJ, O’Neill WW: Role of percutaneous transluminal coronary angioplasty in acute myocardial infarction. American Journal of Cardiology 60:185-187, 1987. [PMID 2955691] 30. Bates ER, Topol EJ, Kline EM, Langburd AB, Fung AY, Walton JA Jr, Bourdillon PDV, Vogel RA, Pitt B, O’Neill WW: Early reperfusion therapy improves left -ventricular function after acute inferior myocardial infarction associated with right coronary artery disease. American Heart Journal 114:261-267, 1987. [PMID 2955688] 31. Sanz ML, Mancini J, LeFree MT, Mickelson JK, Starling MR, Vogel RA, Topol EJ: Variability of quantitative digital subtraction coronary angiography before and -after percutaneous transluminal coronary angioplasty. American Journal of Cardiology 60:55-60, 1987. [PMID 2955693] 32. Topol EJ: Acute intervention for myocardial infarction. Chest 92:929-932, 1987. [PMID 2959455] 33. Topol EJ, Califf RM, Kereiakes DJ, George BS: Thrombolysis and Angio-plasty in Myo-cardial Infarction (TAMI) trial. Journal of the American College of Cardiology 10:65B-74B, 1987. [PMID 2959716] 34. Topol EJ: Clinical use of streptokinase and urokinase therapy for acute myocardial infarction. Heart and Lung 16:760-774, 1987. [PMID 3316129] 35. Papadopoulos SM, Chandler WF, Salamat MS, Topol EJ, Sackellares JC: Recom-binant human tissue-type plasminogen activator therapy in acute thrombotic stroke. Journal of Neurosurgery 67:394-398, 1987. [PMID 3112328] 36. Topol EJ, Califf RM, George BS, Kereiakes DJ, Abbottsmith CW, Candela RJ, 
Lee KL, Pitt B, Stack RS, O’Neill WW and the Thrombo-lysis and Angioplasty in Myocardial Infarction (TAMI) Study Group: A random-ized trial of immediate -versus delayed elective angio-plasty after intravenous tissue plasminogen activator in acute myo-cardial infarction. New England Journal of Medicine 317:581-588, 1987. [PMID 2956516] 37. Topol EJ, Juni JE, O’Neill WW, Nicklas JM, Shea MJ, Burek K, Pitt B:  Exercise testing three days after onset of acute myocardial infarc-tion.  American Journal of Cardiology 60:958-962, 1987. [PMID 2960230] 38. Topol EJ, Bates ER, Walton JA Jr, Baumann G, Wolfe S, Maino J, Bayer L, Gorman L, Kline EM, O’Neill WW: Community hospital administration of intra-venous tissue plasminogen acti-vator in acute myocardial infarction: improved -timing, thrombo-lytic efficacy and ventricular function. Journal of the American College of Cardiology 10:1173-1177, 1987. [PMID 3119685] 39. Topol EJ: Advances in thrombolytic therapy for acute myocardial infarction. Journal of Clinical Pharmacology 27:735-745, 1987. [PMID 3123526] 40. Guerci AD, Gerstenblith G, Brinker JA, Chandra NC, Gottlieb SO, Bahr RD, 
Weiss JL, Shapiro EP, Flaherty JT, Bush DE, Chew PH, Gottlieb SH, Halperin HR, Ouyang P, Walford GD, Bell WR, Fatterpaker AK, Llewellyn M, Topol EJ, Healy B, Siu C, Becker LC, Weisfeldt ML: A randomized trial of intravenous tissue plasminogen activator for acute myocardial infarction with subsequent randomi-zation to elective coronary angioplasty. New England Journal of Medicine 317:1613-1617, 1987. [PMID 2960897] 41. Topol EJ, George BS, Kereiakes DJ, Candela RJ, Abbottsmith CW, Stump DC, Boswick J, O’Neill WW, Stack RS, Califf RM, and the TAMI Study Group: Comparison of two dose regimens of intra-venous tissue plasminogen activator for acute myocardial infarction. American Journal of Cardiology 61:723-728, 1988. [PMID 2965504] 42. Grines CL, Topol EJ, Bates ER, Juni JE, O’Neill WW: Infarct vessel status after intravenous tissue plasminogen activator and acute coronary angio-plasty: Prediction of clinical outcome. American Heart Journal 115:1-7, 1988. [PMID 2962478] 43. O’Neill WW, Topol EJ, Pitt B: Reperfusion therapy of acute myocardial infarction. Progress in Cardiovascular Diseases 30:235-266, 1988. [PMID 3275989] 44. Humphrey LS, Topol EJ, Rosenfeld GI, Borkon AM, Baumgartner WA, Gardner TJ, Maruschak G, Weiss JL: Immediate enhancement of left ventricular relaxation by coronary artery bypass grafting: intraoperative assessment. Circulation 77:886-896, 1988. [PMID 3258195] 45. Topol EJ, Burek K, O’Neill WW, Kewman DG, Kander NH, Shea MJ, Schork A, Kirscht J, Juni JE, Pitt B: A randomized controlled trial of hospital discharge three days after myocardial infarction in the era of reperfusion. New England Journal of Medicine 318:1083-1088, 1988. [PMID 3281014] 46. Kereiakes DJ, Topol EJ, George BS, Abbottsmith CW, Stack RS, Candela RJ, O’Neill WW, Martin LH, Califf RM, and the TAMI Study Group: Emergency coronary artery bypass surgery preserves global and regional left ventricular function after intravenous tissue plasminogen activator therapy for acute myocardial infarction. Journal of the American College of Cardiology 11:899-907, 1988. [PMID 2965716] 47. Califf RM, Topol EJ, George BS, Boswick J, Lee KL, Stump D, Dillon J, Abbottsmith C, Candela R, Kereiakes D, O’Neill W, Stack RS, and the TAMI Study Group: Characteris-tics and outcome of patients in whom reperfusion with intravenous tissue-type plasminogen activator fails: results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) I trial. Circulation 77:1090-1099, 1988. [PMID 2966016] 48. Topol EJ, Califf RM, George BS, Kereiakes DJ, Rothbaum D, Candela RJ, Abbottsmith CW, Pinkerton CA, Stump DC, Collen D, Lee KL, Pitt B, Kline EM, Boswick J, O’Neill WW, Stack RS, and the TAMI Study Group: Coronary arterial thrombolysis with combined infusion of recombinant tissue-type plasminogen -activator and urokinase in patients with acute myocardial infarction. Circulation 77:1100-1107, 1988. [PMID 2966017] 49. Califf RM, O’Neill W, Stack RS, Aronson L, Mark DB, Mantell S, George BS, Candela RJ, Kereiakes DJ, Abbottsmith C, Topol EJ and the TAMI Study Group: Failure of simple clinical measurements to predict perfusion status after intravenous thrombo-lysis. Annals of Internal Medicine 108:658-662, 1988. [PMID 3128953] 50. Topol EJ, Nicklas JM, Kander N, Walton JA, Ellis SG, Gorman L, Pitt B: Coronary revasculariza-tion after intravenous tissue plasmino-gen activator for unstable angina pectoris: results of a randomized, double-blind, placebo-controlled trial. American Journal of Cardiology 62:368-371, 1988. [PMID 2970776] 51. Stump DC, Topol EJ, Chen AB, Hopkins A, Collen D: Monitoring of hemostasis parameters during coronary thrombolysis with recombi-nant tissue-type plasminogen activator. Thrombosis and Haemostasis 59:133-137, 1988. [PMID 2455358] 52. Topol EJ: The long-term investment of coronary angioplasty for acute myocardial infarction. Journal of the American College of Cardiology 11:1150-1152, 1988. [PMID 2966835] 53. Grines CL, O’Neill WW, Anselmo EG, Juni JE, Topol EJ: Compari-son of left -ventricular function and contractile reserve after successful recanalization by thrombolysis versus rescue percutaneous transluminal coronary angioplasty for acute myocardial infarction. American Journal of Cardiology 62:352-357, 1988. [PMID 2970774] 54. Topol EJ: An overview of the Thrombolysis and Angioplasty in acute Myo-cardial Infarction (TAMI) trials. Archives des Maladies du Coeur et des Vaisseaux 81(Suppl I):45-49, 1988. [PMID 2973302] 55. Carlson SE, Aldrich MS, Greenberg HS, Topol EJ: Intracerebral hemorrhage complicat-ing intravenous tissue plasminogen activator treatment. Archives of -Neurology 45:1070-1073, 1988. [PMID 3140769] 56. Ellis SG, Topol EJ, Gallison L, Grines CL, Langburd AB, Bates ER, Walton JA Jr, O’Neill WW: Predictors of success for coronary angioplasty performed for acute myocardial infarction. Journal of the American College of Cardiology 12:1407-1415, 1988. [PMID 2973481] 57. Califf RM, Topol EJ, Stump D, George BS, Boswick JM, Abbottsmith C, Candela R, Kereiakes D, O’Neill W, Stack RS and the TAMI Study Group: Hemorrhagic complica-tions associated with the use of intravenous tissue plasminogen activator in treatment of acute myocardial infarction. American Journal of Medicine 85:353-359, 1988. [PMID 3137818] 58. Werns SW, Topol EJ: Review of hardware for PTCA. Journal of Interventional Cardiology 1:209-219, 1988. 59. Topol EJ, Califf RM, George BS, Kereiakes DJ, Lee KL, for the TAMI Study Group: Insights derived from the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) trials. Journal of the American College of Cardiology 12(Suppl A):24A-31A, 1988. [PMID 2973486] 60. Steinberg EP, Topol EJ, Sakin JW, Kahane SN, Appel LJ, Powe, Anderson GF, Erickson JE, Guerci AD: Cost and procedure implica-tions of thrombo-lytic treatment for acute myocardial infarction. Journal of the American College of Cardiology 12(Suppl A):58A-68A, 1988. [PMID 3057037] 61. Langburd AB, Topol EJ, Sereika SM, Bates ER, Walton JA Jr, Schork MA, Pitt B, O’Neill WW: Determinants of left ventricular functional recovery after thrombolytic therapy and/or immediate coronary angioplasty in acute myocardial infarction. Journal of Interven-tional Cardiology 2:167-174, 1988. 62. Bates ER, O’Neill WW, Topol EJ: Percutaneous atherectomy catheters. Cardiology Clinics 6:373-382, 1988. [PMID 3073007] 63. Topol EJ: Coronary angioplasty for acute myocardial infarction. Annals of Internal Medicine 109:970-980, 1988. [PMID 2973762] 64. Bates ER, Califf RM, Stack RS, Aronson L, George BS, Candela RJ, Kereiakes DJ, Abbottsmith CW, Anderson L, Pitt B, O’Neill WW, Topol EJ, and the Thrombolysis and Angioplasty in Myocardial Infarction Study Group: Thrombolysis and Angioplasty in Myocardial Infarction (TAMI-1) Trial: Influence of infarct location on arterial patency, left ventricular func-tion, and mortality after intravenous tissue plasminogen activator. Journal of the American College of Cardiology 13:12-18, 1989. [PMID 2521226] 65. Topol EJ: Emerging strategies for failed percutaneous transluminal coronary angioplasty. American Journal of Cardiology 63:249-250, 1989. [PMID 2521274] 66. Topol EJ, George BS, Kereiakes DJ, Stump DC, Candela RJ, Abbottsmith CW, Aronson L, Pickel A, Boswick JM, Lee KL, Ellis SG, Califf RM and the TAMI Study Group: A randomized controlled trial of intra-venous tissue plasminogen -activator and early intravenous heparin in acute myo-cardial infarction. Circulation 79:281-286, 1989. [PMID 2492454] 67. Ellis SG, Gallison L, Grines CL, Langburd AB, Bates ER, Walton JA Jr., O’Neill WW, Topol EJ: Incidence and predictors of early recurrent ischemia after successful -percutaneous transluminal coronary angioplasty for acute myocardial infarction. American Journal of Cardiology 63:263-268, 1989. [PMID 2521536] 68. Nicklas JM, Topol EJ, Kander N, O’Neill WW, Walton JA, Ellis S, Gorman L, 
Pitt B: Randomized, double-blind, placebo-controlled trial of tissue plasminogen activator in unstable angina. Journal of the American College of Cardiology 13:434-441, 1989. [PMID 2492325] 69. Holland K, O’Neill WW, Bates ER, Pitt B, Topol EJ: Emergency percutaneous transluminal coronary angio-plasty during acute myocardial infarction for patients more than 70 years of age. American Journal of Cardiology 63:399-403, 1989. [PMID 2521765] 70. Loscalzo J, Wharton TP, Kirshenbaum JM, Levine HJ, Flaherty JT, Topol EJ, Ramaswamy K, Kosowsky BD, Salem DN, Ganz P, Brinker JA, Gurewich V, Muller JE, and the Pro-urokinase for Myocardial Infarction Study Group: Clot-selective coronary thrombolysis with pro-urokinase. Circula-tion 79:776-782, 1989. [PMID 2494004] 71. Ellis SG, O’Neill WW, Bates ER, Walton JA, Nabel EG, Topol EJ: Coronary angioplasty as primary therapy for acute myocardial infarction 6 to 48 hours after symptom onset: Report of an initial experience. Journal of the American College of Cardiology 13:1122-1126, 1989. [PMID 2522467] 72. Bates ER, Topol EJ: Thrombolytic therapy for acute myocardial infarction. Chest 95:257S-264S, 1989. [PMID 2523296] 73. Ellis SG, Shaw R, Gershony G, Thomas R, Roubin GS, Douglas JS, Topol EJ, Stertzer SH, Myler RK, King SB: Risk factors, time course, and treatment effect for restenosis after successful percutaneous transluminal coronary angioplasty of chronic total occlusion. American Journal of Cardiology 63:897-901, 1989. [PMID 2522727] 74. Ellis SG, Topol EJ: Intracoronary stents: will they fulfill their promise as an -adjunct to angioplasty? Journal of the American College of Cardiology 13:1425-1430, 1989. [PMID 2522960] 75. Ellis SG, O’Neill WW, Bates EB, Walton JA, Nabel EG, Werns SW, Topol EJ: Implica-tions for patient triage from survival and left ventricular functional recovery analyses in 500 patients treated with coronary angioplasty for acute myocardial infarction. Journal of the American College of Cardiology 13:1251-1259, 1989. [PMID 2522954] 76. Topol EJ, Califf RM: Tissue plasminogen activator: Why the backlash? Journal of the American College of Cardiology 13:1477-1480, 1989. [PMID 2498415] 77. Muller D, Ellis SG, Topol EJ: Atherectomy of the left main coronary artery with percutaneous cardiopulmonary bypass support. American Journal of Cardiology 64:114-116, 1989. [PMID 2787097] 78. Bates ER, Topol EJ: Early hospital discharge in the myocardial reperfusion era. Clinical Cardiology 12:65-70, 1989. [PMID 2691143] 79. Kereiakes DJ, Topol EJ, Califf RM, George BS, Abbottsmith CW, Stack RS, -Candela RJ, Anderson LC and the TAMI Study Group: Favorable early and long term prognosis following coronary bypass surgery therapy for myocardial infarction: results of a multicenter trial. American Heart Journal 118:199-207, 1989. [PMID 2526573] 80. Kander NH, O’Neill W, Topol EJ, Gallison L, Mileski R, Ellis SG: Long term -follow-up of patients treated with coronary angioplasty for acute myocardial infarction. American Heart Journal 118:228-233, 1989. [PMID 2526574] 81. Grines CL, Topol EJ, Califf RM, Stack RS, George BS, Kereiakes D, Boswick JM, O’Neill WW and the TAMI Study Group: Prognostic implications and predictors of enhanced regional wall motion of the noninfarct zone after thrombolysis and angioplasty therapy of acute myocardial infarction. Circulation 80:245-253, 1989. [PMID 2526697] 82. Stump DC, Califf RM, Topol EJ, Sigmon K, Thornton D, Masek R, Anderson L, Collen D, and the TAMI Study Group: Pharmacodynamics of thrombolysis with recombinant tissue-type plasminogen activator. Correlation with characteristics of and clinical outcomes in patients with acute myocardial infarction. Circulation 80:1222-1230, 1989. [PMID 2509104] 83. Topol EJ: Recombinant tissue plasminogen activator: implications in therapy. Seminars in Hematology and Oncology 26(Suppl 3):25-31, 1989. [PMID 2508227] 84. Topol EJ, Ellis SG, Califf RM, George BS, Stump DC, Bates ER, Nabel EG, 
Walton JA, Candela RJ, Kline EM, Pitt B, and the Thrombolysis and Angio-plasty in Myocardial Infarction (TAMI) Study Group: Combined tissue-type plasmin-ogen activator and prostacyclin therapy for acute myocardial infarc-tion. Journal of the American College of Cardiology 14:877-884, 1989. [PMID 2528903] 85. Ellis SG, Topol EJ, George BS, Kereiakes DJ, Debowey D, Sigmon KN, Pickel A, Lee KL, Califf RM: Recurrent ischemia without warning. Analysis of risk factors for in-hospital ischemic events following successful thrombolysis with intravenous tissue plasminogen activator. Circulation 80:1159-1165, 1989. [PMID 2509102] 86. Holmes DR, Topol EJ: Reperfusion momentum: lessons from the randomized -trials of immediate coronary angioplasty for acute myocardial infarction. Journal of the American College of Cardiology 14:1572-1578, 1989. [PMID 2809019] 87. Gacioch GM, Topol EJ: Sudden paradoxical clinical deterioration during angioplasty of the occluded right coronary artery in acute myocardial infarction. Journal of the American College of Cardiology 14:1202-1209, 1989. [PMID 2808974] 88. Califf RM, Topol EJ, Gersh B: From myocardial salvage to patient salvage in acute myocardial infarction: The role of reperfusion therapy. Journal of the American College of Cardiology 14:1382-1388, 1989. [PMID 2681322] 89. Chapekis AT, Burek K, Topol EJ: The cost:benefit ratio of acute intervention for myocardial infarction: results of a prospective, matched pair analysis. American Heart Journal 118:878-882, 1989. [PMID 2510487] 90. Ellis SG, Shaw RE, King SB, Myler RK, Topol EJ: Restenosis after excellent angiographic angioplasty result for chronic total coronary artery occlusion –-Implications for newer percutaneous revascularization devices. American Journal of Cardiology 64:667-668, 1989. [PMID 2528903] 91. Muller DWM, Topol EJ: Acute myocardial infarction: early and late percutaneous transluminal coronary angioplasty. Current Opinion in Cardiology 4:524-530, 1989. 92. Topol EJ: Acute myocardial infarction: treatment with thrombolytic therapy. -Clinical Cardiology 7:827-836, 1989. [PMID 2688884] 93. Sane DC, Califf RM, Topol EJ, Stump DC, Mark DB, Greenberg CS: Bleeding during thrombolytic therapy for acute myocardial infarction: mechanisms and -management. Annals of Internal Medicine 111:1010-1022, 1989. [PMID 2688504] 94. Burek K, Kirscht J, Topol EJ: Exercise capacity in patients 3 days after acute, -uncomplicated myocardial infarction. Heart and Lung 18:575-580, 1989. [PMID 2684916] 95. Muller DW, Topol EJ, Califf RM, Sigmon K, George BS, Kereiakes DJ, Candela RJ, Ellis SG, and the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group: Relationship between antecedent angina pectoris and short-term prognosis after thrombolytic therapy for acute myocardial infarction. American Heart Journal 119:224-231, 1990. [PMID 2405608] 96. Popma JJ, Topol EJ: Factors influencing restenosis after coronary angioplasty. American Journal of Medicine 88:16N-24N, 1990. [PMID 2195881] 97. Kander NH, Holland KJ, Pitt B, Topol EJ: A randomized pilot trial of brief versus prolonged heparin after successful reperfusion in acute myocardial infarction. American Journal of Cardiology 65:139-142, 1990. [PMID 2404389] 98. Vogel R, Shawl F, Tommaso CL, O’Neill W, Overlie P, O’Toole J, Vandormael M, Topol EJ, Tabari KK, Vogel J, Smith S, Friedmann R, White C, George B, Tierstein P: Initial report of the national registry of elective cardiopulmonary bypass supported coronary angioplasty. Journal of the American College of Cardiology 15:23-29, 1990. [PMID 2404047] 99. Topol EJ, Wilson VE: The pivotal role of early and sustained infarct vessel patency in patients with acute myocardial infarction. Heart and Lung 19:584-593, 1990. [PMID 2228647] 100. Muller DWM, Topol EJ: Unresolved issues: late reperfusion, lytic failure, and reocclusion. Coronary Artery Disease 1:39-49, 1990. [PMID 10148970] 101. Califf RM, Topol EJ, George BS, Kereiakes DJ, Aronson LG, Martin L, Candela R, Abbottsmith CW, O’Neill WW, Stack RS and the TAMI Study Group: One-year outcome after therapy with tissue plasminogen activator: report from the Thrombolysis and Angioplasty in Acute Myocardial Infarction trial. American Heart Journal 119:777-785, 1990. [PMID 2108575] 102. Kavanaugh KM, Topol EJ: Acute intervention during myocardial infarction in -patients with prior coronary bypass surgery. American Journal of Cardiology 65:924-926, 1990. [PMID 2321545] 103. Topol EJ: Ultrathrombolysis. Journal of the American College of Cardiology 15:922-924, 1990. [PMID 2107238] 104. Muller DWM, Topol EJ: Protected coronary angioplasty: minimizing the hazards of high risk coronary interventions. Journal of Invasive Cardiology 2:103-107, 1990. [PMID 10148970] 105. Sutton JM, Topol EJ: Usefulness of coronary artery angioplasty strategies in acute myocardial infarction. Canadian Journal of Cardiology 6:111-122, 1990. [PMID 2187576] 106. Ellis SG, Muller DW, Topol EJ: Possible survival benefit from con-comitant beta –but not calcium – antagonist therapy during reperfusion for acute myocardial infarction. American Journal of Cardiology 66:125-128, 1990. [PMID 1973588] 107. Williams DO, Topol EJ, Califf RM, Roberts R, Mancini J, Joelson JM, Ellis SG: Intravenous recombinant tissue-type plasminogen activator in patients with -unstable angina pectoris. Results of a placebo-controlled, randomized trial. -Circulation 82:376-383, 1990. [PMID 2115407] 108. George BS, Candela RJ, Topol EJ, Stack RS, Kereiakes DJ, Abbottsmith CW, Masek R, Pickel A, Dillon J, Harrelson L, Califf RM, and the TAMI Study Group: Brachial approach to emergency cardiac catheteriza-tion during thrombolytic thera-py for acute myocardial infarc-tion. Catheterization and Car-diovascular Diagnosis 20:221-226, 1990. [PMID 2119888] 109. O’Connor CM, Califf RM, Massey EW, Mark DB, Kereiakes DJ, Candela RJ, Abbottsmith C, George B, Stack RS, Aronson L, Mantell S, Topol EJ: Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis. Journal of the American College of Cardiology 16:533-540, 1990. [PMID 2117618] 110. Ohman EM, Califf RM, Topol EJ, Candela RJ, Abbottsmith CW, Ellis SG, 
Sigmon KN, Kereiakes DJ, George BS, Stack RS and the TAMI Study Group: Conse-quences of reocclusion follow-ing successful reperfusion ther-apy in acute myocardial infarction. Circulation 82:781-791, 1990. [PMID 2394002] 111. Abbottsmith CW, Topol EJ, George BS, Stack RS, Kereiakes DJ, Candela RJ, Anderson LC, Harrelson-Woodlief L, Califf RM: Fate of patients with acute myocardial infarction with patency of the infarct-related vessel achieved with successful thrombolysis versus rescue angioplasty. Journal of the American College of Cardiology 16:770-778, 1990. [PMID 1698843] 112. Ellis SG, Topol EJ: Results of percutaneous transluminal coronary angioplasty of high risk angulated stenoses. American Journal of Cardiology 66:932-937, 1990. [PMID 2220615] 113. Muller DWM, Topol EJ, George BS, Kereiakes DJ, Aronson LG, Lee KL, Abbottsmith CW, Ellis SG, Califf RM, and the TAMI Study Group: Two year -outcome following angiographically documented myocardial reperfusion for acute coronary occlusion. American Journal of Cardiology 66:796-801, 1990. [PMID 2220575] 114. Popma JJ, Topol EJ: Accelerated, combined, and adjunctive thrombolytic strategies for acute myocardial infarction. Current Opinion in Cardiology 5:482-489, 1990. 115. Muller DWM, Ellis SG, Debowey DL, Topol EJ: Quantitative angiographic -comparison of the immediate success of coronary angioplasty, coronary atherectomy and endoluminal stenting. American Journal of Cardiology 66:938-942, 1990. [PMID 2220616] 116. Ellis SG, Vandormael MG, Cowley MJ, DiSciascio G, Deligonul U, Topol EJ, 
Bulle TM: Coronary morphologic and clinical determinants of procedural outcome with angioplasty for multivessel coronary disease: implications for patient selection. Circulation 82:1193-1202, 1990. [PMID 2401060] 117. Topol EJ: Can thrombolysis be improved? Hospital Formulary 25:19-22, 1990. 118. Califf RM, Harrelson-Woodlief L, Topol EJ: Left ventricular ejection fraction 
may not be useful as an endpoint for thrombolytic therapy comparative trials. -Circulation 82:1847-1853, 1990. [PMID 2225381] 119. Wall TC, Califf RM, Harrelson-Woodlief L, Mark DM, Honan M, Abbottsmith CW, Candela R, Berrios E, Phillips HR, Topol EJ, and the TAMI study group: Usefulness of a pericardial friction rub after thrombolytic therapy during acute myocardial infarction in predicting amount of myocardial damage. American -Journal of Cardiology 66:1418-1421, 1990. [PMID 2123603] 120. Bates ER, Clemmensen PM, Califf RM, Gorman LE, Aronson LG, George BS, Kereiakes DJ, Topol EJ and the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group: Precordial ST segment depression predicts a worse prognosis in inferior infarction despite reperfusion therapy. Journal of the American College of Cardiology 16:1538-1544, 1990. [PMID 2123903] 121. Muller DWM, Topol EJ: Selection of patients with acute myocardial infarction 
for thrombolytic therapy. Annals of Internal Medicine 113:949-960, 1990. [PMID 2240919] 122. Sane DC, Stump DC, Topol EJ, Sigmon KN, Clair WK, Kereiakes DJ, George BS, Stoddard MF, Bates ER, Stack RS, Califf RM, and the Thrombolysis and Angio-plasty in Myocardial Infarction Study Group: Racial differences in responses to thrombolytic therapy with recombinant tissue-type plasminogen activator. Increased fibrin(ogen)olysis in blacks. Circulation 83:170-175, 1991. [PMID 1898641] 123. Ellis SG, Cowley MJ, DiSciascio G, Deligonul U, Topol EJ, Bulle TM, Vandormael MG: Determinants of 2-year outcome after coronary angioplasty in patients with multivessel disease on the basis of comprehensive preprocedural evaluation: Implications for patient selection. Circulation 83:1905-1914, 1991. [PMID 2040043] 124. Schatz RA, Baim DS, Leon M, Ellis SG, Goldberg S, Hirshfeld JW, Cleman MW, Cabin HS, Walker C, Stagg J, Buchbinder M, Teirstein PS, Topol EJ, Savage M, Perez J, Curry RC, Whitworth H, Sousa JE, Tio F, Almagor Y, Ponder R, Penn IM, Leonard B, Levine SL, Fish RD, Palmaz JC: Clinical experience with the Palmaz-Schatz coronary stent: initial results of a multicenter study. Circulation 83:148-161, 1991. [PMID 1984878] 125. Clemmenson P, Bates ER, Califf RM, Hlatky M, Aronson L, George BS, Lee KL, Kereiakes DJ, Gacioch G, Berios E, Topol EJ, and the TAMI Study Group: -Complete atrioventricular block complicating inferior wall acute myocardial infarction treated with reperfusion therapy. American Journal of Cardiology 67:225-230, 1991. [PMID 1899319] 126. Topol EJ: Promises and pitfalls of new devices for coronary artery disease. -Circulation 83:689-694, 1991. [PMID 1991385] 127. Nabel EG, Topol EJ, Galeana A, Ellis SG, Bates ER, Werns SW, Walton JA, 
Muller DA, Schwaiger M, Pitt B: A randomized placebo-controlled trial of combined early intravenous captopril and recombinant tissue-type plasminogen activator therapy in acute myocardial infarction. Journal of the American College of Cardiology 17:467-473, 1991. [PMID 1825097] 128. Kereiakes DJ, Topol EJ, George BS, Stack RS, Abbottsmith CW, Ellis S, Candela RJ, Harrelson L, Martin LH, Califf RM, and the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group: Myocardial infarction with minimal coronary atherosclerosis in the era of myocardial reperfusion. Journal of the American College of Cardiology 17:304-312, 1991. [PMID 1899433] 129. Popma JJ, Dick RJL, Haudenschild CC, Topol EJ, Ellis SG: Atherectomy of right coronary ostial stenoses: initial and long-term results, technical features and histologic findings. American Journal of Cardiology 67:431-433, 1991. [PMID 1994670] 130. Ellis SG, Debowey D, Kline E, Bates ER, Topol EJ: Treatment of recurrent ischemia after thrombolysis and successful reperfusion for acute myocardial infarction: effect on in-hospital mortality and left ventricular function. Journal of the American -College of Cardiology 17:752-757, 1991. [PMID 1993797] 131. Topol EJ: Thrombolysis: go with the flow? Chest 99:529-530, 1991. [PMID 1704825] 132. Lincoff AM, Popma JJ, Vogel R, Ellis SG, Topol EJ: Percutaneous support devices for high risk or complicated coronary angioplasty. Journal of the American College of Cardiology 17:770-780, 1991. [PMID 1993799] 133. Topol EJ, Ellis SG: Coronary collaterals revisited: accessory pathway to myocardial preservation during infarction. Circulation 83:1084-1086, 1991. [PMID 1999011] 134. Dick RJL, Haudenschild CC, Popma JJ, Ellis SG, Muller DW, Topol EJ: Directional atherectomy for total coronary occlusions. Coronary Artery Disease 2:189-199, 1991. 135. Topol EJ, Califf RM: Intravenous heparin, thrombolytics and medical marketing. Journal of Interventional Cardiology 4:1-4, 1991. 136. Stewart RE, Kander N, Juni JE, Ellis SG, O’Neill WW, Schork MA, Topol EJ, Schwaiger M: Submaximal exercise Thallium-201 SPECT for assessment of interventional therapy in patients with acute myocardial infarction. American Heart Journal 121:1033-1041, 1991. [PMID 1901189] 137. Muller DWM, Topol EJ, Ellis SG, Sigmon KN, Lee K, Califf RM, and the Thromboly-sis and Angioplasty in Myocardial Infarction (TAMI) Study Group: Multivessel coronary artery disease: a key predictor of short-term prognosis following reperfusion therapy for acute myocardial infarction. American Heart -Journal 121:1042-1049, 1991. [PMID 1901190] 138. Sutton JM, Topol EJ: Significance of a negative exercise thallium test in the -presence of a critical residual stenosis after thrombolysis for acute myocardial infarction. Circulation 83:1278-1286, 1991. [PMID 1901529] 139. Mark DB, Sigmon K, Topol EJ, Kereiakes DJ, Pryor DB, Candela RJ, Califf RM: Identification of acute myocardial infarction patients suitable for early hospital discharge after aggressive interventional therapy. Results from the Thrombolysis and Angioplasty in Acute Myocardial Infarction registry. Circulation 83:1186-1193, 1991. [PMID 2013140] 140. Muller DWM, Ellis SG, Topol EJ: Colchicine and antineoplastic therapy for the prevention of restenosis after percutaneous coronary interventions. Journal of the American College of Cardiology 17:126B-131B, 1991. [PMID 2016470} 141. Califf RM, Topol EJ, Stack RS, Ellis SG, George BS, Kereiakes DJ, Samaha JK, Worley SJ, Anderson JL, Harrelson-Woodlief L, Wall TC, Phillips HR, Abbottsmith CW, Candela RJ, Wilson B, Sasahara AA, Mantell SJ, Lee KL, for the TAMI study group: Evaluation of combination thrombolytic therapy and timing of cardiac catheterization in acute myocardial infarction. Results of Thrombo-lysis and Angioplasty in Myocardial Infarction–Phase 5 randomized trial. Circulation 83:1543-1556, 1991. [PMID 1902405] 142. Ellis SG, Bates ER, Schaible T, Weisman H, Pitt B, Topol EJ: Prospects for the 
use of antagonists to the platelet glycoprotein IIb/IIIa receptor to prevent post-angioplasty restenosis and thrombosis. Journal of the American College of Cardi-ology 17:89B-95B, 1991. [PMID 2016487] 143. Topol EJ, Holmes DR, Rogers WJ: Coronary angiography after thrombolytic therapy for acute myocardial infarction. Annals of Internal Medicine 114:877-885, 1991. [PMID 2014950] 144. Schatz RA, Goldberg S, Leon M, Baim D, Hirshfeld J, Cleman M, Ellis S, Topol EJ: Clinical experience with the Palmaz-Schatz Coronary Stent. Journal of the American College of Cardiology 17:155B-159B, 1991. [PMID 2016473] 145. Topol EJ: Integration of anticoagulation, thrombolysis and coronary angioplasty for unstable angina pectoris. American Journal of Cardiology 68:136-141, 1991. [PMID 1892061] 146. Califf RM, George BS, Ohman EM, Quigley PJ, Topol EJ, Kereiakes DJ, Harrelson L, Candela RJ, Flanagan C, Stack RS: The use of intraaortic balloon pumping as an adjunct to reperfusion therapy in acute myocardial infarction. American Heart Journal 121:895-901, 1991. [PMID 1900381] 147. Topol EJ, Agnelli G: Strategies for administration of tissue plasminogen activator. Molecular Biology and Medicine 8:219-234, 1991. [PMID 1806764] 148. Morris JA, Muller DWM, Topol EJ: Combination thrombolytic therapy: a comparison of simultaneous and sequential regimens of tissue plasminogen activator and urokinase. American Heart Journal 122:375-380, 1991. [PMID 1907086] 149. Sane DC, Stump DC, Topol EJ, Sigmon K, Kereiakes DJ, George BS, Mantell SJ, Macy E, Collen D, Califf RM: Correlation between baseline plasminogen activator inhibitor levels and clinical outcome during therapy with tissue plasminogen activator for acute myocardial infarction. Thrombosis and Haemostasis 65:275-279, 1991. [PMID 1904653] 150. Popma JJ, Topol EJ: Adjuncts to thrombolysis for myocardial reperfusion. -Annals of Internal Medicine 115:34-44, 1991. [PMID 1675557] 151. Kereiakes DJ, Califf RM, George BS, Ellis S, Samaha J, Stack RS, Martin LC, Young SY, Topol EJ, and the TAMI Study Group: A comparison of emergency and deferred coronary bypass surgery following intravenous thrombolytic therapy for acute myocardial infarction. Circulation 79:281-286, 1989. [PMID 2492454] 152. Kereiakes DJ, Califf RM, George BS, Ellis S, Samaha J, Stack R, Martin LH, Young S, Topol EJ, and the TAMI Study Group: Coronary bypass surgery improves global and regional left ventricular function following thrombolytic therapy for acute myocardial infarction. American Heart Journal 122:390-399, 1991. [PMID 1907087] 153. Dellborg M, Topol EJ, Swedberg K: Dynamic QRS complex and ST segment vectorcardiographic monitoring can identify vessel patency in patients with acute myocardial infarction treated with reperfusion therapy. American Heart Journal 122:943-948, 1991. [PMID 1927880] 154. Topol EJ: Which thrombolytic agent should one choose? Progress in Cardio-vascular Disease 34:165-178, 1991. [PMID 1947122] 155. Popma JJ, Califf RM, Topol EJ: Clinical trials of restenosis after coronary angioplasty. Circulation 84:1426-1436, 1991. [PMID 1884465] 156. Muller DWM, Topol EJ, Ellis SG, Harrelson-Woodlief LG, Sigmon KN, Kereiakes DJ, George BS, Worley SJ, Samaha JK, Phillips H III, Califf RM and the TAMI 5 Study Group: Determinants of the need for early acute intervention in patients treated conservatively following thrombolytic therapy for acute myocardial infarction. Journal of the American College of Cardiology 18:1594-1601, 1991. [PMID 1960302] 157. Ellis SG, De Cesare NB, Pinkerton CA, Whitlow P, King SB III, Chazzal ZMB, Kereiakes DJ, Popma JJ, Menke KK, Topol EJ, Holmes DR: Relation of stenosis morphology and clinical presentation to the procedural results of directional coronary atherectomy. Circulation 84:644-653, 1991. [PMID 1860208] 158. Muller DWM, Topol EJ: Implantable devices in the coronary artery: From metal to genes. Trends in Cardiovascular Medicine 1:225-232, 1991. 159. Dick RJ, Popma JJ, Muller DW, Burek K, Topol EJ: In-hospital costs associated with new percutaneous coronary devices. American Journal of Cardiology 68:879-885, 1991. [PMID 1927947] 160. Bates ER, Topol EJ: Limitations of thrombolytic therapy for acute myocardial infarction complicated by congestive heart failure and cardiogenic shock. Journal of American College of Cardiology 18:1077-1084, 1991. [PMID 1894853] 161. Tenaglia AN, Califf RM, Candela RJ, Kereiakes DJ, Berrios E, Stack RS, 
Topol EJ: Thrombolytic therapy in patients requiring cardiopulmonary resuscitation. American Journal of Cardiology 68:1015-1019, 1991. [PMID 1927913] 162. Kirshenbaum JM, Bahr RD, Flaherty JT, Gurewich V, Levine HJ, Loscalzo J, Schumacher R, Topol EJ, Wahr D, Braunwald E and the Pro-urokinase for -Myocardial Infarction Study Group: Clot-selective coronary thrombolysis with low-dose synergistic combinations of single-chain urokinase-type plasminogen -activator and recombinant tissue-type plasminogen activator. American Journal of Cardiology 68:1564-1569, 1991. [PMID 1746455] 163. Muller DM, Ellis SG, Topol EJ: Experimental models of coronary artery restenosis. Journal of American College of Cardiology 19:418-432, 1992. [PMID 1732371] 164. Wall TC, Califf RM, George BS, Ellis SG, Samaha J, Kereiakes DJ, Worley SJ, Sigmon K, Topol EJ for the TAMI 7 Study Group: Accelerated plasminogen -activator dose regimens for coronary thrombolysis. Journal of the American -College of Cardiology 19:482-489, 1992. [PMID 1537998] 165. Ellis SG, Myler RK, King SB, Douglas JS, Topol EJ, Shaw RE, Stertzer SH, 
Roubin GS: Causes and correlates of death after unsupported coronary angioplasty: Implications for the use of angioplasty and advanced support techniques in high-risk settings. American Journal of Cardiology 68:1447-1451, 1991. [PMID 1746425] 166. Gacioch GM, Ellis SG, Lee L, Bates ER, Kirsh M, Walton JA, Topol EJ: Cardiogenic shock complicating acute myocardial infarction: the use of coronary angioplasty and the integration of the new support devices into patient management. Journal of the American College of Cardiology 19:647-653, 1992. [PMID 1538023] 167. Popma JJ, Califf RM, Ellis SG, George BS, Kereiakes DJ, Samaha JK, Worley SJ, Anderson JL, Stump D, Woodlief L, Sigmon K, Wall TC, Topol EJ: Mechanism of benefit of combination thrombolytic therapy for acute myocardial infarction: a quantitative angiographic and hematologic study. Journal of the American -College of Cardiology 20:1305-12, 1992. [PMID 1430679] 168. Muller DWM, Shamir KJ, Ellis SG, Topol EJ: Peripheral vascular complications after conventional and complex percutaneous coronary interventional procedures. American Journal of Cardiology 69:63-68, 1992. [PMID 1729869] 169. Holmes DR, Garratt KN, Topol EJ: Coronary angioplasty versus excisional atherectomy trial: CAVEAT. International Journal of Cardiology 35:143-146, 1992. [PMID 1572733] 170. Popma JJ, De Cesare NB, Ellis SG, Holmes DR, Pinkerton CA, Whitlow P, 
King SB III, Chazzal ZMB, Topol EJ, Garratt KN, Kereiakes DJ: Clinical, angiographic and procedural correlates of quantitative coronary dimensions after directional coronary atherectomy. Journal of the American College of Cardiology 18:1183-1189, 1991. [PMID 1918694] 171. Topol EJ, Califf RM, Vandormael M, Grines CL, George BS, Sanz ML, Wall T, O’Brien M, Schwaiger M, Aguirre FV, Young S, Popma JJ, Lee KL, Ellis SG and the Thrombolysis and Angioplasty in Myocardial Infarction-6 Study Group: A randomized trial of late reperfusion therapy for acute myocardial infarction. -Circulation 85:2090-2099, 1992. [PMID 1591828] 172. Muller DWM, Topol EJ: Thrombolytic therapy: Adjuvant mechanical intervention for acute myocardial infarction. American Journal of Cardiology 69:60A-70A, 1992. [PMID 1729880] 173. Lincoff AM, Popma JJ, Hacker JA, Ellis SG, Topol EJ: Abrupt vessel closure -complicating coronary angioplasty: clinical, angiographic and therapeutic profile. Journal of the American College of Cardiology 19:926-935, 1992. [PMID 1552113] 174. Rosenschein U, Haudenschild CC, Dick RJ, Watkins JF, Ellis SG, Yakubov SJ, Topol EJ: Histopathologic correlates of coronary lesion angiographic morphology: lessons from a directional atherectomy experience. Coronary Artery Disease 3:953-961, 1992. 175. Popma JJ, Topol EJ, Hinohara T, Pinkerton CA, Baim DS, King SB, Holmes DR Jr, Whitlow PL, Kereiakes DJ, Hartzler GO, Kent KM, Ellis SG, Simpson JB for the U.S. Directional Atherectomy Investigator Group: Abrupt closure after directional coronary atherectomy. Journal of the American College of Cardiology 19:1372-1379, 1992. [PMID 1593028] 176. Califf RM and Topol EJ for the GUSTO Investigators: Thrombolytic therapy for myocardial infarction: a perspective of clinical trialists. Clinical Cardiology 15:143-144, 1992. [PMID 1551260] 177. Ellis SG, Van de Werf F, Ribeiro-daSilva E, Topol EJ: Present status of rescue coronary angioplasty: current polarization of opinion and randomized trials. - -Journal of the American College of Cardiology 19:681-686, 1992. [PMID 1531664] 178. Ver Lee PN, Muller DWM, Popma JJ, Ellis SG, Topol EJ: A comparison of clinical and quantitative angiographic outcomes of coronary stenting in elective and emergency settings: a single center experience. Coronary Artery Disease 2:945-951, 1991. 179. Ellis SG, Myler RK, King SB, Douglas JS, Topol EJ, Shaw RE, Stertzer SH, 
Roubin GS, Murphy, MC: Causes and correlates of death after unsupported coronary angioplasty: implications for use of angioplasty and advanced support techniques in high-risk settings. American Journal of Cardiology 68:1447-1451, 1991. [PMID 1746425] 180. Chapman GD, Ohman EM, Topol EJ, Candela RJ, Kereiakes DJ, Samaha J, Berrios E, Pieper K, Young S, Califf RM: Minimizing the risk of inappropriately administering thrombolytic therapy (Thrombolysis and Angioplasty in Myocardial Infarction [TAMI] Study Group). American Journal of Cardiology 71:783-787, 1993. [PMID 8456754] 181. Ellis SG, Savage M, Fischman D, Leon M, Goldberg S, Hirshfeld JW, Baim DS, Cleman MW, Teirstein PS, Walker C, Bailey S, Topol EJ, Schatz RA: Restenosis after placement of Palmaz-Schatz stents in native coronary arteries: initial results of a multicenter experience. Circulation 86:1836-1844, 1992. [PMID 1451256] 182. De Cesare NB, Popma JJ, Holmes DR Jr, Dick RJ, Whitlow PL, King SB, 
Pinkerton CA, Kereiakes DJ, Topol EJ, Haudenschild CC, Ellis SG: Excision beyond the “normal” arterial lumen: Clinical, angiographic and histologic correlates of ectasia after directional coronary atherectomy. American Journal of Cardiology 69:314-319, 1992. [PMID 1734641] 183. Arnold AZ, Topol EJ: Assessment of reperfusion after thrombolytic therapy for myocardial infarction. American Heart Journal 124:441-447, 1992. [PMID 1636587] 184. Topol EJ: The status of research in invasive cardiology. Journal of Invasive -Cardiology 4:10-17, 1992. [PMID 10149902] 185. Granger CB, Califf RM, Topol EJ: Thrombolytic therapy for acute myocardial infarction. Drugs 44:293-325, 1992. [PMID 1382931] 186. Topol EJ, Califf RM: Answers to complex questions cannot be derived from “simple” trials. British Heart Journal 68:348-351, 1992. [PMID 1449915] 187. Wall TC, Califf RM, Ellis SG, Sigmon K, Kereiakes D, George BS, Samaha J, 
Sane D, Stump D, Stack RS, Topol EJ: Lack of impact of early catheterization and fibrin specificity on bleeding complications after thrombolytic therapy. Journal of the American College of Cardiology 21:597-603, 1993. 188. Popma JJ, De Cesare NB, Pinkerton CA, Kereiakes DJ, Whitlow P, King SB, 
Topol EJ, Holmes DR, Leon MB, Ellis SB: Quantitative analysis of factors influencing late lumen loss and restenosis after directional coronary atherectomy. American Journal of Cardiology 71:552-557, 1993. [PMID 8438740] 189. Topol EJ, Armstrong P, Van de Werf F, Kleiman N, Lee K, Morris D, Simmons M, Barbash G, White H, Califf RM on behalf of the GUSTO Steering Committee: Confronting the issues of patient safety and investigator conflict of interest in an international clinical trial of myocardial reperfusion. Journal of American College of Cardiology 19:1123-1128, 1992. [PMID 1564212] 190. Rosenschein U, Yakubov SJ, Guberinich D, Bach DS, Sonda PL, Abrams GD, Topol EJ: Shock wave thrombus ablation, a new method for noninvasive mech-anical thrombolysis. American Journal of Cardiology 70:1358-1361, 1992. [PMID 1442591] 191. Schwartz RS, Holmes DR, Topol EJ: The restenosis paradigm revisited: An -alternative proposal for cellular mechanisms. Journal of the American College of Cardiology 20:1284-1293, 1992. [PMID 1401633] 192. Williamson BD, Muller DWM, Topol EJ: Should older patients with acute -myocardial infarction receive thrombolytic therapy? Drugs and Aging 2:462-468, 1992. [PMID 1493350] 193. Grambow DW, Topol EJ: Effect of maximal medical therapy on refractoriness 
of unstable angina pectoris. American Journal of Cardiology 70:577-581, 1992. [PMID 1354937] 194. Granger CB, Califf RM, Young S, Candela R, Samaha J, Worley S, Kereiakes DJ, Topol EJ: Outcome of patients with diabetes mellitus and acute myocardial infarction treated with thrombolytic therapy. Journal of the American College of Cardiology 21:920-925, 1993. [PMID 8450161] 195. Topol EJ, Califf RM: Thrombolytic therapy for elderly patients. New England Journal of Medicine 327:45-46, 1992. [PMID 1598101] 196. Doorey AJ, Michelson E, Topol EJ: Thrombolytic therapy of acute myocardial infarction: Keeping the unfulfilled promises. Journal of the American Medical -Association 268:3108-3114, 1992. [PMID 1433742] 197. Sutton JM, Topol EJ: Left ventricular function assessment and acute myocardial infarction: The role of left ventricular imaging in establishing diagnosis, prognosis and therapeutic benefit. Current Opinion in Cardiology 7:1035-1045, 1992. 198. Ellis SG, Tcheng JE, Navetta FI, Muller DW, Weisman HF, Smith C, Anderson KM, Califf RM, Topol EJ. Safety and antiplatelet effect of murine monoclonal antibody 7E3 Fab directed against platelet glycoprotein IIb/IIIa in patients undergoing elective coronary angioplasty. Coronary Artery Disease 2:167-175, 1993. 199. The GUSTO Angiographic Investigators. The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and survival after acute myocardial infarction. The New England Journal of Medicine 329:1615-1622, 1993. [PMID 8232430] 200. The EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. The New England Journal of Medicine 330:956-961, 1994. [PMID 8121459] 201. Ellis SG, Mooney MR, George BS, Ribeiro da Silva EE, Talley JD, Flanagan WH, Topol EJ: Randomized trial of late elective angioplasty versus conservative management for patients with residual stenoses after thrombolytic treatment of myocardial infarction. Circulation 86:1400-1406, 1992. 
[PMID 1423952] 202. Muller DWM, Topol EJ, Abrams GD, Gallagher KP, Ellis SG: Intramural methotrexate therapy for the prevention of neointimal thickening after balloon angioplasty. Journal of the American College of Cardiology 20:460-466, 1992. [PMID 1386089] 203. Rosenschein U, Ellis SG, Haudenschild CC, Yakubov SJ, Muller DWM, Dick RJ, Topol EJ. Comparison of histopathologic coronary lesions obtained from directional atherectomy in stable angina versus acute coronary syndromes. American Journal of Cardiology 73:508-510, 1994. 204. Lincoff AM, Topol EJ, Chapekis AT, George BS, Candela RJ, Muller DWM, Zimmerman CA, Ellis SG: Intracoronary stenting compared with conventional therapy for abrupt vessel closure complicating coronary angioplasty: a matched case-control study. Journal of the American College of Cardiology 21:866-875, 1993. [PMID 8450155] 205. Topol EJ: The restenosis “antitheory”. Mayo Clinic Proceedings 68:88-90, 1993. [PMID 8417263] 206. Kalff V, Hicks RJ, Hutchins G, Topol EJ, Schwaiger M: Use of carbon-11 acetate and dynamic positron emission tomography to assess regional myocardial oxygen consumption in patients with acute myocardial infarction receiving thrombolysis or coronary angioplasty. American Journal of Cardiology 71:529-535, 1993. [PMID 8438738] 207. Topol EJ, Ellis SG, Cosgrove DM, Bates ER, Muller DWM, Schork N, Schork MA, Loop FD: Analysis of coronary angioplasty practice in the United States -using a private insurance database. Circulation 87:1489-1497, 1993. [PMID 8141866] 208. Casale PN, Whitlow PL, Franco I, Grigera F, Pashkow FJ, Topol EJ: Comparison of major complication rates with new atherectomy devices for percutaneous coronary intervention in women versus men. American Journal of Cardiology 71:1221-1223, 1993. [PMID 8480650] 209. Kleiman NS, Ohman ME, Califf RM, George B, Kereiakes D, Aquirre F, Weisman H, Schaible T, Topol EJ: Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy: Results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 Pilot Study. Journal of the American College of Cardiology 22:381-389, 1993. [PMID 8335808] 210. Harrison JK, Califf RM, Harrelson-Woodlief L, Kereiakes D, George BS, Stack RS, Ellis SG, Lee KL, O’Neill W, Topol EJ, and the TAMI Study Group: Systolic left ventricular function after reperfusion therapy for acute myocardial infarction: An analysis of determinants of improvement. Circulation 87:1531-1541, 1993. [PMID 8491008] 211. Topol EJ: Rotablator to the rescue. American Journal of Cardiology 71:858-859, 1993. [PMID 8456767] 212. Topol EJ: Cardiac intervention in the elderly: State-of-the-art 1993. Cardiology in the Elderly I:51-53, 1993. 213. Topol EJ, Bonan R, Kakkar VV, de Bono D, Rothman M, Willerson J, Dewart D, Ganz P, Strony J, Cohen M, Raymond R, Fox I, Maraganore J, Adelman B: Use of an antithrombin, Hirulog, in place of heparin during coronary angioplasty. Circulation 87:1622-1629, 1993. [PMID 8491018] 214. Lee KS, Topol EJ, Stewart WJ: Atypical presentation of papillary fibroelastoma mimicking multiple vegetations in a woman with suspected subacute bacterial endo--carditis. American Heart Journal 125:1443-1445, 1993. [PMID 8480605] 215. de Feyter PJ, van Suylen RJ, de Jaegere PPT, Topol EJ, Serruys PW: Interventional techniques for the treatment of lesions in saphenous venous bypass grafts. Journal of the American College of Cardiology 21:1539-1549, 1993. [PMID 8496517] 216. Lincoff AM, Topol EJ: Trickle down thrombolysis. Journal of the American -College of Cardiology 21:1396-1398, 1993. [PMID 8473647] 217. Krucoff MW, Croll MA, Pope JE, Granger CB, O’Connor Cm, Sigmon KN, Wagner BL, Ryan JA, Lee KL, Kereiakes DJ, Samaha JK, Worley SJ, Ellis SG, Wall TC, Topol EJ, Califf RM, for the TAMI 7 Study Group: Continuous 12-Lead ST segment recovery analysis: A noninvasive method for real time detection of failed myocardial reperfusion. Circulation 88:437-446, 1993. [PMID 8339407] 218. Rosenschein U, Ellis SG, Yakubov SJ, Haudenschild CC, Dick RJ, Topol EJ: Histopathologic correlates of coronary lesion angiographic morphology: Lessons from a directional atherectomy experience. Coronary Artery Disease 3:953-961, 1992. 219. Lincoff AM, Topol EJ: The illusion of reperfusion. Does anyone achieve optimal myocardial reperfusion? Circulation 87:1792-1805 and 88:1361-1374, 1993. [PMID 8353902] 220. Flaherty JT, Pitt B, Gruber JW, Heuser RR, Rothbaum DA, George BS, Burwell LR, Kereiakes DJ, Deitchman D, Gustafson N, Brinker JA, Becker LC, Mancini GBJ, Topol EJ, Werns SW: Recombinant human superoxide dismutase (h-SOD) fails to improve recovery of ventricular function in patients undergoing coronary angioplasty for acute myocardial infarction. Circulation 89:1982-1991, 1994. [PMID 8181121] 221. Nath FC, Muller DWM, Rosenschein U, Ellis SG, Topol EJ: Heparin monitoring during coronary intervention: Activated clotting time versus activated partial thromboplastin time. Canadian Journal of Cardiology 9:797-801, 1993. [PMID 8281479] 222. MacIssac A, Thomas J, Topol EJ: Toward the quiescent coronary artery plaque. 
Journal of the American College of Cardiology 22:1228-1241, 1993. [PMID 8104965] 223. Ellis SG, Tcheng JT, Navetta FI, Muller DWM, Weisman HG, Smith C, Anderson K, Califf RM, Topol EJ: Safety and antiplatelet effect of fab murine monoclonal antibody 7E3 fab directed against platelet glycoprotein IIb/IIIa in patients undergoing elective coronary angioplasty – an initial experience. Coronary Artery -Disease 4:167-175, 1992. [PMID 8269208] 224. Sane DC, Califf RM, Sigmon KN, Topol EJ, Stump DC: Effect of heparin admin-istration on fibrinogenolysis during thrombolytic therapy with tissue plasminogen activator for acute myocardial infarction. Fibrinolysis 7:103-107, 1993. 225. Nath FC, Muller DWM, Ellis SG, Rosenschein U, Chapekis A, Quain L, Zimmerman C, Topol EJ: Thrombosis of a flexible coil coronary stent: frequency, predictors and clinical outcome. Journal of the American College of Cardiology 21:622-627, 1993. [PMID 8436743] 226. Topol EJ, Plow EF: Clinical trials of platelet receptor inhibitors. Thrombosis and Haemostasis 70:94-98, 1993. [PMID 8236122] 227. Douglas JS, Pepine CJ, Block PC, Brinker JA, Johnson WL, Klinke WP, Levin DC, Mullins CE, Nissen SE, Topol EJ, Ullyot DJ, Vetrovec GW, Vogel JHK: Recom-mendations for development and maintenance of competence in coronary interventional procedures. Journal of the American College of Cardiology 22:629-631, 1993. [PMID 8335841] 228. Ohman EM, Christenson RH, Califf RM, George BS, Samaha JK, Kereiakes DJ, Worley SJ, Wall TC, Berrios E, Sigmon KN, Lee K, Topol EJ, and the TAMI 7 Study Group: Noninvasive detection of reperfusion after thrombolysis based on serum creatine kinase MB changes and clinical variables. American Heart Journal 126:819-826, 1993. [PMID 8213437] 229. Lincoff AM, Califf RM, Ellis SG, Sigmon KN, Lee KL, Topol EJ for the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group: Thrombolytic therapy for women with myocardial infarction: Is there a gender gap? Journal of the American College of Cardiology 22:1780-1787, 1993. [PMID 8245328] 230. Topol EJ, Leya F, Pinkerton CA, Whitlow PL, Hofling B, Simonton CA, Masden RR, Serruys PW, Leon MB, Williams DO, King SB, Mark DB, Isner JM, Holmes DR, Ellis SG, Lee KL, Keeler G, Berdan LG, Hinohara T, Califf RM, on behalf of the CAVEAT Study Group: A comparison of coronary angioplasty with directional atherectomy in patients with coronary artery disease. New England Journal of Medicine 329:221-227, 1993. [PMID 8316266] 231. Bernardi MM, Califf RM, Kleiman N, Ellis SG, Topol EJ: Lack of usefulness of prolonged bleeding times in predicting hemorrhagic events in patients receiving the 7E3 glycoprotein IIb/IIIa platelet antibody. American Journal of Cardiology 72:1121-1125, 1993. [PMID 8237799] 232. DeFranco AC, Topol EJ: Invasive strategies for acute myocardial infarction in the elderly. Cardiology in the Elderly 2:274-289, 1994. 233. Brown DL, Topol EJ: Stroke complicating percutaneous coronary revascularization. American Journal of Cardiology 72:1207-1209, 1993. [PMID 8237818] 234 Cosgrove DM, Topol EJ: Perspectives on percutaneous coronary revascularization. Seminars in Thoracic and Cardiovascular Surgery 6:65-66, April, 1994. 235. Thomas JD, Topol EJ: Wanted: Dead or alive. Assessment of myocardial viability post thrombolysis. Circulation 88:797-799, 1993. [PMID 8339439] 236. The GUSTO Investigators: An international randomized trial com-paring four thrombolytic strategies for acute myocardial infarction. New England Journal of Medicine 329:673-682, 1993. [PMID 8204123] 237. George BS, Voorhees WD, Roubin GS, Fearnot NE, Pinkerton CA, Raizner AE, King SB, Holmes DR, Topol EJ, Kereiakes DJ, Hartzler GO: Multicenter investigation of coronary stenting to treat acute or threatened closure after percutaneous transluminal coronary angioplasty: Clinical and angiographic outcomes. Journal of the American College of Cardiology 22:135-143, 1993. [PMID 8509533] 238. Topol EJ, Califf RM: Scorecard cardiovascular medicine. Annals of Internal -Medicine 120:65-70, 1994. [PMID 8250458] 239. Baim DS, Hinohara T, Holmes D, Topol EJ, Pinkerton C, King SB, Whitlow P, Kereiakes D, Farley B, Simpson JB for the U.S. Directional Coronary Atherectomy Investigator Group: Results of directional coronary atherectomy during multicenter pre-approval testing. American Journal of Cardiology 72:6E-11E, 1993. [PMID 8213572] 240. Lefkovits J, Topol EJ: Future direction in thrombolysis for myocardial infarction: what are the unanswered questions? Coronary Artery Disease 5:306-316, 1994. [PMID 8044342] 241. Ohman EM, Topol EJ, Califf RM, Bates ER, Ellis SG, Kereiakes D, Geroge B, Samaha JK, Kline E, Sigmon KN, Stack RS and the Thrombolysis Angioplasty in Myocardial Infarction Study Group: An analysis of the cause of early mortality after administration of thrombolytic therapy. -Coronary Artery Disease 4:957-964,1993. [PMID 8173712] 242. Topol EJ, Califf RM, Lee KL on behalf of the GUSTO Investigators: The irony of biased editors who write editorials. British Journal of Clinical Practice 47:283-284, 1993. [PMID 8015584] 243. Sgarbossa EB, Topol EJ: Semantic ambiguity, the “non-”nosology and myocardial infarction. Journal of Clinical Epidemiology 47:441-446,1994. [PMID 7730869] 244. Villa AE, Guzman LA, Chen W, Golomb G, Levy RJ, Topol EJ: Local delivery of dexamethasone for prevention of neointimal proliferation in a rat model of balloon arterial injury. Journal of Clinical Investigation 93:1243-1249, 1994. [PMID 8132764] 245. Cowley MJ, Vandermael M, Topol EJ, Whitlow PL, D


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